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We’re deep into a biochemical soup here…for simplicity this is how I am thinking of it…short chain fatty acids are very good for the gut and are appearing to be neuroprotective to the brain but maybe the brain just doesn’t like to burn them due to the neurons’ inability to survive the byproducts. So perhaps the benefit of the SCFAs to… Read more

No I have not. But I also know that if you don’t get enough sleep every night (4 to 5 sleep cycles) then these will accumulate. Poor sleep seems to be at the root of cognitive decline (called now type 3 diabetes) as well as insulin resistance. Sleep and eat well – gee, maybe mom was right? Luckily we don’t see (recognize or measure)… Read more

I understand that a healthy human microbiome can metabolize soluble fibre and resistant starch to short chain fatty acids as well. This I found fascinating.

I looked up why the brain only uses glucose as fuel and it seems that burning fatty acids (presumably via ketones) produces too many reactive oxygen species and neurons are not adept… Read more

@AngelaM… Great suggestion to gather the data on the spread of the word about the No Grain diet, and the increase in protein in general. I have more than 25 horses belonging to probably as many as 10 owners (one is a yard of 14 horses all on the no grain diet) already trying either the full no grain diet or at least adding the SBM (which i… Read more

Jan and Feb AMA videos are now correct! Thanks for your patience! Go to the forum “Zoom Events” and look for the discussion with the AMA title.

Great point! The brain accepts glucose without the need for insulin. This is called insulin independent glucose uptake. Muscles also have this independent uptake when the cells are in exercise mode (at V O2 Max or approximately 60% of aerobic exercise – under anaerobic levels).

Glucose for the brain comes from liver glycogen storage and… Read more

I’ll look into it as well and see what I can find about what we know from first principles. It’s been a while (read decades) since I looked at this stuff so a refresher would be a good idea. I know on some of the podcasts you have said that burning glucose is a “dirty” process but that it’s the preferred fuel of the brain so those two… Read more

From what I understand, the burning of glucose is a less efficient process than burning fat (free fatty acid or FFA) in the mitochondrial electron transport chain / Krebs cycle. The FFA releases 20 to 28 times more energy than it does from glucose. And in the process, free radicals are formed from oxidizing glucose that need to… Read more

Hi @Matt-Support I’m trying to find the replay for the February AMA. The link which I am replying to here (which came through with the email notification for the next Rounds) doesn’t seem to work. Also I think the January AMA was named as the February AMA by mistake. I have listened to the January AMA but would like to listen to that again… Read more

Thank you!!

Our next trim is in a couple of weeks-will let you know.

Specifically I am asking about using something that is supposed to kill the fly (which takes time through paralysis of breathing) as a repellent. It doesn’t make sense to me since the purpose of a repellent is to make the fly not land in the first place.

Most fly sprays we have seem to try to kill the fly (albeit a delayed effect), but it… Read more